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Filtered Search Results
Medchemexpress LLC SU14813 maleate | 849643-15-8 | MFCD24682713 | 99.0% | 558.56 | C27H31FN4O8 | 10 MG
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SU14813 maleate is a multi-targeted receptor tyrosine kinase inhibitor provided for research use. It shows low-nanomolar inhibitory activity against VEGFR2, VEGFR1, PDGFRβ, and KIT, and is supplied as a solid or as a 10 mM solution in DMSO for laboratory studies.
- Multi-target RTK inhibition with low-nanomolar potency.
- Activity data reported for VEGFR2, VEGFR1, PDGFRβ, and KIT.
- Available as solid packs and a 10 mM DMSO solution for easy preparation.
- High reported purity appropriate for in vitro and preclinical research.
- Supplied with SDS documentation for safe laboratory handling.
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Medchemexpress LLC Immh-010 maleate | 2541982-47-0 | 99.8% | 756.04 | 5 MG
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IMMH-010 maleate is a prodrug that acts as a novel PD-L1 inhibitor, showing potential antitumor activity. It is being investigated for the treatment of neurological disorders and advanced malignant solid tumors. Upon oral administration, it quickly converts into its active form, YPD-29B. This compound is significant for advancing research in the field of PD-L1 inhibitors and related therapeutic applications.
- Acts as a novel PD-L1 inhibitor
- Shows potential antitumor activity
- Investigated for neurological disorders and advanced malignant solid tumors
- Converts into active form, YPD-29B, upon oral administration
- Advances research in PD-L1 inhibitors and related therapeutic applications
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Medchemexpress LLC Enalapril maleate (Standard) | 76095-16-4 | 100.0% | 25 MG
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Enalapril maleate (Standard) is an analytical standard and an angiotensin-converting enzyme (ACE) inhibitor. This product is intended for research and analytical applications, serving as a reference standard for assays.
- Reference standard for assay
- Used in qualitative, quantitative, and methodological research
- Applicable for HPLC, GC, and MS applications
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Medchemexpress LLC Dibutyl maleate | 105-76-0 | 99.2% | 228.28 | 50 G
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Dibutyl maleate, the diester of Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. It can enhance contact sensitization to Fluorescein isothiocyanate in mice.
- Can be used as an intermediate of pharmaceutical synthesis.
- Enhances contact sensitization to Fluorescein isothiocyanate in mice.
- For research use only.
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Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mM (in 1mL DMSO)
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( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
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Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100.0% | 1 ML
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Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood-brain barrier (BBB) and exhibits anti-tumor activity. Perhexiline maleate is used in the research of cancers and cardiovascular diseases like angina.
- Orally active CPT1 and CPT2 inhibitor
- Reduces fatty acid metabolism
- Induces mitochondrial dysfunction and apoptosis in hepatic cells
- Can cross the blood-brain barrier (BBB)
- Shows anti-tumor activity
- Useful in research for cancers and cardiovascular diseases like angina
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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 G
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Tegaserod maleate is an orally active compound that functions as a serotonin receptor 4 agonist and a serotonin receptor 2B antagonist. It demonstrates inhibitory activity against 5-HT2A, 5-HT2B, and 5-HT2C receptors. This compound has been observed to induce apoptosis in tumor cells, inhibit PI3K/Akt/mTOR signaling, and reduce S6 phosphorylation. It shows promise for anti-tumor applications and research into irritable bowel syndrome.
- Orally active serotonin receptor 4 agonist.
- Serotonin receptor 2B antagonist.
- Induces tumor cell apoptosis.
- Inhibits PI3K/Akt/mTOR signaling and decreases S6 phosphorylation.
- Exhibits anti-tumor activity, delays tumor growth, reduces metastases, and increases survival.
- Potential for irritable bowel syndrome research.
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Medchemexpress LLC NB-598 (maleate) | 155294-62-5 | MFCD22665748 | 99.4% | 565.74 | C31H35NO5S2 | 10 MG
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NB-598 maleate is a research-grade small molecule that acts as a potent, competitive inhibitor of squalene epoxidase (SE). It is used in biochemical and cell-based studies to suppress triglyceride and sterol biosynthesis via the farnesol pathway and is supplied as the maleate salt in solid form or as a concentrated DMSO solution for assay use.
- Potent competitive inhibitor of squalene epoxidase.
- Used to suppress triglyceride and cholesterol biosynthesis in biochemical studies.
- Supplied as the maleate salt for improved stability and handling.
- Available as small solid quantities and as a 10 mM solution in DMSO for convenience in assays.
- High reported purity (~99.4%) suitable for research applications.
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TARGETMOL CHEMICALS INC --DIZOCILPINE MALEATE 50MG
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Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. purity: 99%
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Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | MFCD30607264 | 99.7% | 673.11 | C34H33ClN6O7 | 10 MG
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Neratinib maleate is the maleate salt of neratinib, an orally available, irreversible inhibitor selective for HER2 and EGFR kinases. Supplied for research use, it is used to probe HER2/EGFR signaling and to evaluate kinase inhibition in preclinical studies.
- Irreversible HER2 and EGFR inhibitor with IC50s of 59 nM (HER2) and 92 nM (EGFR).
- High purity (99.7%) suitable for analytical and biological assays.
- Molecular weight 673.11 and formula C34H33ClN6O7.
- Stable as a solid at 4°C; in solution: -80°C (6 months) or -20°C (1 month), protect from light.
- Available in small milligram pack sizes for research applications.
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Apexbio Technology LLC CGP 3466B maleate 200189-97-5 50mg
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CGP 3466B maleate (CAS 200189-97-5) is a structural derivative of R-( )-Deprenyl but has negligible monoamine oxidase-B inhibitory activity It acts as a neuroprotective agent through inhibition of apoptotic cell death pathways In vitro studies demonstrate that CGP 3466B prevents apoptosis in human neuroblastoma cells PC-12 cells and cerebellar granule cells exposed to cytosine arabinoside In vivo data from the pmn/pmn mouse model of motor neuron disease showed that oral administration of CGP 3466B delayed disease progression maintained motor function and significantly extended survival CGP 3466B is thus under investigation as a potential therapeutic for neurodegenerative conditions
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Sigma Aldrich Fine Chemicals Biosciences 4-Acetoxy-2,5-dimethyl-3(2H)furanone >=95%, FG | 4166-20-5 | MFCD00799462 | 1KG
4-Acetoxy-2,5-dimethyl-3(2H)furanone >=95%, FG | Purity: >=95% | Mol Wt: 170.16 | 4166-20-5 | MFCD00799462 | 1KG
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Medchemexpress LLC HY-12377 5mg Medchemexpress, GSK0660 CAS:1014691-61-2 Purity:>98%
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Medchemexpress, HY-12377 5mg GSK0660 CAS:1014691-61-2 GSK0660 is a potent antagonist of PPARβ and PPARδ, with IC50s of 155 nM for both isoforms. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences 4-Acetoxy-2,5-dimethyl-3(2H)furanone >=95%, FG | 4166-20-5 | MFCD00799462 | 5KG
4-Acetoxy-2,5-dimethyl-3(2H)furanone >=95%, FG | Purity: >=95% | Mol Wt: 170.16 | 4166-20-5 | MFCD00799462 | 5KG
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Sigma Aldrich Fine Chemicals Biosciences Methyl 2-pyrrolecarboxylate 97% | 1193-62-0 | MFCD00817048 | 5G
Methyl 2-pyrrolecarboxylate 97% | Purity: 97% | Mol Wt: 125.13 | 1193-62-0 | MFCD00817048 | 5G
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